SCHEMBL618095

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL618252	0.87	LMNA (0.39)	SMN1; SMN2TP53MEN1KMT2APRNP
	SCHEMBL615767	0.87	CYP1A1 (0.45)	TP53MEN1KMT2ALMNAALDH1A1
	SCHEMBL618801	0.86	PDE10A (0.43)	SMN1; SMN2LMNAMAPK1USP2S1PR1
	SCHEMBL618114	0.86	CYP1A1 (0.43)	KMT2ALMNAMAPK1USP2S1PR1
	SCHEMBL618973	0.85	KDM4E (0.42)	SMN1; SMN2MEN1KMT2ALMNAMAPK1
	SCHEMBL616060	0.83	PGR (0.42)	SMN1; SMN2MEN1KMT2ALMNAMAPK1
	SCHEMBL618061	0.83	KMT2A (0.38)	CHEK1SMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL618304	0.82	TUBB4A (0.43)	MEN1KMT2ATNFPRNPNOD2
	SCHEMBL618906	0.81	GABRA1 (0.39)	CHEK1SMN1; SMN2LMNAMAPK1USP2
	SCHEMBL618793	0.81	ALDH1A1 (0.43)	MEN1KMT2ALMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.