SCHEMBL618061

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL618906	0.90	GABRA1 (0.39)	CHEK1LMNAUSP2MAPK1S1PR1
	SCHEMBL616544	0.87	NISCH (0.36)	CHEK1S1PR1ALDH1A1MAPTKDM4E
	SCHEMBL615767	0.85	CYP1A1 (0.45)	KMT2AMEN1TUBB1LMNAALDH1A1
	SCHEMBL618252	0.85	LMNA (0.39)	KMT2AMEN1LMNAUSP2MAPK1
	SCHEMBL618793	0.84	ALDH1A1 (0.43)	KMT2AMEN1TUBB1LMNAALDH1A1
	SCHEMBL16471515	0.83	MAPK1 (0.36)	KMT2AMEN1TUBB1LMNAUSP2
	SCHEMBL618114	0.83	CYP1A1 (0.43)	KMT2ALMNAUSP2MAPK1S1PR1
	SCHEMBL618095	0.83	CHEK1 (0.41)	KMT2AMEN1PTGDR2CHEK1LMNA
	SCHEMBL618801	0.83	PDE10A (0.43)	LMNAUSP2MAPK1S1PR1ALDH1A1
	SCHEMBL618973	0.83	KDM4E (0.42)	KMT2AMEN1TUBB1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.