Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938200 | 0.78 | RAB9A (0.47) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL11656026 | 0.73 | NPC1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| Phthalic Acid SCHEMBL30933129 | 0.71 | ALDH1A1 (0.70) | MAPTSMN1; SMN2HPGDALDH1A1TDP1 | |
| Phthalic Acid SCHEMBL5874671 | 0.71 | ALDH1A1 (0.70) | MAPTSMN1; SMN2HPGDALDH1A1TDP1 | |
| Phthalic Acid SCHEMBL5874678 | 0.71 | ALDH1A1 (0.70) | MAPTSMN1; SMN2HPGDALDH1A1TDP1 | |
| SCHEMBL10712470 | 0.71 | BACE1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| Ethylamine SCHEMBL28129048 | 0.70 | ACMSD (0.46) | NPC1RAB9AHPGDCASP3SENP8 | |
| SCHEMBL6516769 | 0.70 | RAB9A (0.45) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| Benzene SCHEMBL28200229 | 0.70 | TSHR (0.52) | NPC1RAB9ASMN1; SMN2HPGDCASP3 | |
| SCHEMBL5114023 | 0.70 | MAPT (0.47) | NPC1RAB9AMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849738-B2 | Processes for the production of thienopyrimidine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-02-01 | — | — | US | disclosed |
| US-20030055269-A1 | Processes for the production of thienopyrimidine derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1266898-A1 | PROCESSES FOR THE PRODUCTION OF THIENOPYRIMIDINE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055269-A1 | Processes for the production of thienopyrimidine derivatives | GNRHR, NR5A1, DHODH | NPC1 1984/4885RAB9A 3940/4885MAPT 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.