Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159174 | 0.91 | ALDH1A1 (0.36) | CYP2C9MAOAALDH1A1 | |
| SCHEMBL19231108 | 0.82 | — | — | |
| SCHEMBL16867323 | 0.75 | OPRM1 (0.42) | OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL10090559 | 0.74 | ALDH1A1 (0.45) | CYP2C9MAOAALDH1A1 | |
| SCHEMBL7516473 | 0.74 | ALDH1A1 (0.45) | CYP2C9MAOAALDH1A1 | |
| SCHEMBL2658304 | 0.72 | ALDH1A1 (0.42) | OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL4167981 | 0.72 | OPRM1 (0.39) | OPRM1OPRD1OPRK1ALDH1A1EPHX2 | |
| Hydrochloric Acid SCHEMBL2960053 | 0.72 | ALDH1A1 (0.43) | CYP2C9MAOAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2960051 | 0.72 | ALDH1A1 (0.43) | CYP2C9MAOAALDH1A1 | |
| SCHEMBL7733614 | 0.71 | EPHX2 (0.46) | ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503979-A1 | PROCESS FOR HYDROGENATING UNACTIVATED IMINES USING RUTHENIUM COMPLEXES AS CATALYSTS | Abdur-Rashid, Kamaluddin (CA) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097571-A1 | PROCESS FOR HYDROGENATING UNACTIVATED IMINES USING RUTHENIUM COMPLEXES AS CATALYSTS | ABDUR-RASHID KAMALUDDIN (CA) | 2003-11-27 | — | — | WO | disclosed |