SCHEMBL6159174

SCHEMBL6159174

C(CC1CC1)=Nc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MAOA P21397 1/20 0.35
GBA1 P04062 2/20 0.33
HTT P42858 1/20 0.33
MAP1LC3B Q9GZQ8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KMT2A Q03164 3/20 0.32
CYP2C9 P11712 1/20 0.32
MAPT P10636 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
GAA P10253 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6158721 0.91 OPRM1 (0.38) ALDH1A1MAOACYP2C9
SCHEMBL7516473 0.78 ALDH1A1 (0.45) ALDH1A1MAOAHTTKDM4EGLA
SCHEMBL10090559 0.78 ALDH1A1 (0.45) ALDH1A1MAOAHTTKDM4EGLA
Hydrochloric Acid SCHEMBL2960053 0.75 ALDH1A1 (0.43) ALDH1A1MAOAHTTKDM4EGLA
Hydrochloric Acid SCHEMBL2960051 0.75 ALDH1A1 (0.43) ALDH1A1MAOAHTTKDM4EGLA
SCHEMBL10756355 0.71 SIRT2 (0.45) ALDH1A1MAOAKDM4EKMT2ACYP2C9
SCHEMBL11001019 0.71 ALDH1A1 (0.39) ALDH1A1MAOAHTTKDM4EGLA
SCHEMBL1116030 0.71 ALDH1A1 (0.44) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL6299978 0.71 ALDH1A1 (0.39) ALDH1A1MAOAHTTKDM4EGLA
SCHEMBL8148121 0.71 ALDH1A1 (0.39) ALDH1A1MAOAHTTKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1503979-A1 PROCESS FOR HYDROGENATING UNACTIVATED IMINES USING RUTHENIUM COMPLEXES AS CATALYSTS Abdur-Rashid, Kamaluddin (CA) 2005-02-09 EP disclosed
WO-2003097571-A1 PROCESS FOR HYDROGENATING UNACTIVATED IMINES USING RUTHENIUM COMPLEXES AS CATALYSTS ABDUR-RASHID KAMALUDDIN (CA) 2003-11-27 WO disclosed