Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123658 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL6965429 | 0.87 | MAOB (0.65) | ALDH1A1LMNAMAOBMAOAMAPT | |
| SCHEMBL15286510 | 0.87 | ALDH1A1 (0.51) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL5989500 | 0.85 | NPC1 (0.56) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL3134818 | 0.85 | SLC6A3 (0.52) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL13870529 | 0.83 | OPRL1 (0.50) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL3995720 | 0.82 | TSHR (0.50) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL3997587 | 0.82 | FFAR1 (0.50) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL2801838 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRMAPK10 | |
| SCHEMBL8588987 | 0.81 | MAOB (0.57) | ALDH1A1LMNAHSD17B10TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517680-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | Astrazeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000295-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |