Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125285 | 0.82 | NUDT1 (0.37) | SMN1; SMN2PKMKMT2ATP53MAPT | |
| SCHEMBL126959 | 0.68 | SMPD3 (0.35) | SMN1; SMN2KMT2ATP53MAPTPOLB | |
| SCHEMBL7559366 | 0.63 | SMN1; SMN2 (0.40) | SMN1; SMN2PKMKMT2ATP53MAPT | |
| SCHEMBL6156472 | 0.61 | KDM4E (0.57) | MAPTPOLBKDM4EALDH1A1GAA | |
| SCHEMBL1979184 | 0.60 | KDM4E (0.48) | PKMMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL18510395 | 0.60 | CDK1 (0.49) | DYRK1A | |
| SCHEMBL9689711 | 0.59 | BACE1 (0.57) | MAPTPOLBKDM4EALDH1A1GAA | |
| SCHEMBL7515463 | 0.59 | MAPT (0.44) | KMT2AMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL14842870 | 0.57 | MEN1 (0.57) | SMN1; SMN2KMT2AMAPTCYP3A4BLM | |
| SCHEMBL30880797 | 0.57 | MAPT (0.43) | MAPTIRAK4POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040817-B1 | Dyeing composition comprising a pyrazolo(1,5-a)pyrimidine and a monocyclic polyaminopyrimidine as oxidation bases and a coupler, and dyeing process | OREAL (FR) | 2005-02-02 | — | — | EP | claimed |