Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125285 | 0.75 | NUDT1 (0.37) | SMN1; SMN2PKMKMT2AKDM4EALDH1A1 | |
| SCHEMBL33682 | 0.69 | SMPD3 (0.31) | SMN1; SMN2KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL24103795 | 0.66 | TSHR (0.36) | SMN1; SMN2KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL6159780 | 0.63 | SMN1; SMN2 (0.34) | SMN1; SMN2PKMKMT2AKDM4EALDH1A1 | |
| SCHEMBL1232073 | 0.62 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL30128490 | 0.62 | KDM4E (0.49) | SMN1; SMN2KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL7375160 | 0.62 | KDM4E (0.49) | SMN1; SMN2KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL6156472 | 0.61 | KDM4E (0.57) | KDM4EALDH1A1TSHRMAPK1POLB | |
| Hydrochloric Acid SCHEMBL31352102 | 0.61 | ALDH1A1 (0.32) | PKMALDH1A1MAPT | |
| SCHEMBL4953168 | 0.61 | MKNK1 (0.40) | KDM4EALDH1A1TSHRPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | disclosed |