Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | AANAT | Q16613 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158570 | 0.89 | CASP1 (0.49) | CASP1MTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL6157870 | 0.89 | CASP1 (0.56) | CASP1MTNR1AMEN1KMT2A | |
| SCHEMBL6157542 | 0.89 | MTNR1A (0.49) | CASP1MTNR1AMEN1KMT2AMAPT | |
| SCHEMBL6157421 | 0.88 | CASP1 (0.41) | CASP1MTNR1AMEN1KMT2AMAPT | |
| SCHEMBL6157558 | 0.80 | KMT2A (0.48) | CASP1MTNR1AKMT2ATSHRMAPT | |
| SCHEMBL7487986 | 0.74 | CASP1 (0.55) | CASP1MAPK1GAA | |
| SCHEMBL2824958 | 0.70 | AANAT (0.67) | CASP1MTNR1AAANATMEN1KMT2A | |
| SCHEMBL10575207 | 0.69 | MEN1 (0.68) | CASP1MTNR1AAANATMEN1KMT2A | |
| SCHEMBL13560942 | 0.69 | MEN1 (0.66) | CASP1MTNR1AAANATMEN1KMT2A | |
| SCHEMBL761155 | 0.68 | MTNR1A (0.76) | MTNR1AAANATMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |