Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | SPR | P35270 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157870 | 0.94 | CASP1 (0.56) | CASP1SPRMTNR1ANOTUMMTNR1B | |
| SCHEMBL6157542 | 0.90 | MTNR1A (0.49) | CASP1MTNR1ANOTUMMTNR1BMEN1 | |
| SCHEMBL6159833 | 0.89 | CASP1 (0.54) | CASP1MTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL6157421 | 0.83 | CASP1 (0.41) | CASP1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL7483717 | 0.76 | NOTUM (0.41) | SPRMTNR1ANOTUMMTNR1BMEN1 | |
| SCHEMBL7483705 | 0.75 | HTR1A (0.40) | ACHEBCHEHTR2A | |
| SCHEMBL6157558 | 0.74 | KMT2A (0.48) | CASP1MTNR1AMTNR1BKMT2AHPGD | |
| SCHEMBL30952643 | 0.69 | MTNR1A (0.71) | SPRMTNR1ANOTUMMTNR1BMEN1 | |
| SCHEMBL7487986 | 0.69 | CASP1 (0.55) | CASP1MAPK1 | |
| SCHEMBL28872473 | 0.67 | SPR (0.62) | SPRMTNR1ANOTUMMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |