Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160554 | 0.86 | FKBP1A (0.39) | KMT2AALDH1A1EPHX2FKBP1AADORA3 | |
| SCHEMBL6159879 | 0.80 | ALDH1A1 (0.40) | KMT2AALDH1A1EPHX2 | |
| SCHEMBL6330492 | 0.76 | GPR119 (0.36) | KMT2AALDH1A1EPHX2FKBP1AADORA3 | |
| SCHEMBL6159433 | 0.75 | CCKBR (0.47) | EPHX2ADORA3 | |
| SCHEMBL6159409 | 0.71 | CCKBR (0.46) | EPHX2ADORA3 | |
| SCHEMBL6158527 | 0.71 | PPARG (0.39) | KMT2ACYP3A4 | |
| SCHEMBL6159791 | 0.70 | EPHX2 (0.34) | KMT2AALDH1A1EPHX2 | |
| SCHEMBL6161308 | 0.69 | EPHX2 (0.39) | KMT2AALDH1A1EPHX2FKBP1A | |
| SCHEMBL6159631 | 0.68 | CCKBR (0.53) | KMT2ATSHR | |
| SCHEMBL6339911 | 0.68 | CCKBR (0.44) | KMT2AALDH1A1EPHX2FKBP1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |