Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160212 | 0.74 | SPHK1 (0.45) | SPHK1ITGB3ITGA2BHRH3NPC1 | |
| SCHEMBL8632718 | 0.71 | CYP2C9 (0.45) | SPHK1ITGB3ITGA2BHRH3SMN1; SMN2 | |
| SCHEMBL8632715 | 0.71 | HRH3 (0.43) | SPHK1ITGB3ITGA2BHRH3 | |
| SCHEMBL8635435 | 0.71 | SPHK1 (0.42) | SPHK1ITGB3ITGA2BHRH3NPC1 | |
| SCHEMBL1648624 | 0.67 | MAPT (0.64) | MAPTKMT2A | |
| SCHEMBL4435638 | 0.67 | ITGB3 (0.46) | ITGB3ITGA2BHRH3DPP4DPP8 | |
| SCHEMBL7334680 | 0.66 | CHKA (0.52) | ITGB3ITGA2BHRH3DPP4DPP8 | |
| SCHEMBL7364014 | 0.66 | CHKA (0.44) | SPHK1ITGB3ITGA2BHRH3DPP4 | |
| SCHEMBL7329592 | 0.66 | CHKA (0.47) | ITGB3ITGA2BHRH3DPP4DPP8 | |
| SCHEMBL25845893 | 0.65 | LGMN (0.55) | ITGB3ITGA2BNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549622-A1 | SULFONYLBENZODIAZEPINONE ACETAMIDES AS BRADYKININ ANTAGONISTS | Elian Pharmaceuticals Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033436-A1 | SULFONYLBENZODIAZEPINONE ACETAMIDES AS BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC (US) | 2004-04-22 | — | — | WO | disclosed |