Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159046 | 0.92 | DRD2 (0.60) | SIGMAR1MMP3PARP14PARP10 | |
| SCHEMBL3890408 | 0.85 | SIGMAR1 (0.62) | SIGMAR1MMP3ALDH1A1LMNAGAA | |
| SCHEMBL8216873 | 0.83 | APP (0.55) | SIGMAR1ALDH1A1LMNAAPP | |
| SCHEMBL6163074 | 0.82 | HRH3 (0.47) | SIGMAR1MMP3PARP14PARP10HRH3 | |
| SCHEMBL14064421 | 0.81 | TRPV6 (0.70) | SIGMAR1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL7474955 | 0.81 | ALDH1A1 (0.66) | MMP3ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL7478048 | 0.81 | MMP3 (0.45) | SIGMAR1MMP3ALDH1A1LMNAGAA | |
| SCHEMBL12041706 | 0.80 | S1PR1 (0.69) | SIGMAR1MMP3ALDH1A1LMNAGAA | |
| SCHEMBL7477521 | 0.79 | CHRM4 (0.59) | SIGMAR1MMP3HRH3 | |
| SCHEMBL381548 | 0.79 | S1PR1 (0.67) | SIGMAR1MMP3ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |