Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166693 | 0.87 | CA12 (0.34) | ALDH1A1KMT2AHTTLMNAGAA | |
| SCHEMBL6162781 | 0.78 | PRNP (0.49) | ALDH1A1KMT2ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6163264 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KMT2ARAB9AL3MBTL1HTT | |
| SCHEMBL15700636 | 0.74 | KIF11 (0.40) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL12438531 | 0.70 | ALOX15 (0.42) | ALDH1A1HTTTSHRLMNAGAA | |
| SCHEMBL11739657 | 0.70 | ALOX15 (0.42) | ALDH1A1HTTTSHRLMNAGAA | |
| SCHEMBL12707509 | 0.70 | ALOX15 (0.42) | ALDH1A1HTTTSHRLMNAGAA | |
| SCHEMBL110806 | 0.70 | ALOX15 (0.42) | ALDH1A1HTTTSHRLMNAGAA | |
| SCHEMBL112490 | 0.70 | ALOX15 (0.42) | ALDH1A1HTTTSHRLMNAGAA | |
| SCHEMBL110807 | 0.70 | ALOX15 (0.42) | ALDH1A1HTTTSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934310-B1 | THIO ACID DERIVED MONOCYCLIC N-HETEROCYCLICS AS ANTICOAGULANTS | SCHERING AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-6221886-B1 | Thio acid derived monocyclic N-heterocyclics as anticoagulants | BERLEX LABORATORIES, INC. | 2001-04-24 | — | — | US | disclosed |
| US-6166014-A | Thio acid derived monocyclic N-heterocyclics as anticoagulants | BERLEX LABORATORIES, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| US-6162807-A | Thio acid derived monocyclic N-heterocyclics as anticoagulants | BERLEX LABORATORIES, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-6150382-A | ENZYME INHIBITORS OF BLOOD COAGULATION FACTOR XA, A SERINE PROTEASE CLASS OF ENZYMES; E.G., 4-HYDROXY-3-((4-(2-CARBOXY-METHYL)THIO-6-(3-(1-METHYL)-6-(3-(1 -METHYL)IMIDAZOLIN-2-YL)-PHENOXY-3,5-DIFLUOROPYRIDINE AND DERIVATIVES | BERLEX LABORATORIES, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-6034084-A | CARDIOVASCULAR DISORDERS | BERLEX LABORATORIES, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-6004985-A | BLOOD-COAGULATION FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0934310-A1 | THIO ACID DERIVED MONOCYCLIC $i(N)-HETEROCYCLICS AS ANTICOAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015547-A1 | THIO ACID DERIVED MONOCYCLIC N-HETEROCYCLICS AS ANTICOAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |