Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | METAP2 | P50579 | 5/20 | 0.39 |
| ▸ | METAP1 | P53582 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CAD | P27708 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655937 | 1.00 | ALOX15 (0.42) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL110808 | 1.00 | ALOX15 (0.42) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL110806 | 1.00 | ALOX15 (0.42) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL12438531 | 1.00 | ALOX15 (0.42) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| Hydrochloric Acid SCHEMBL8853654 | 0.98 | ALOX15 (0.41) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| Hydrochloric Acid SCHEMBL1564997 | 0.98 | ALOX15 (0.41) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| Hydrochloric Acid SCHEMBL8853645 | 0.98 | ALOX15 (0.41) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| Hydrochloric Acid SCHEMBL1564995 | 0.98 | ALOX15 (0.41) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| Hydrochloric Acid SCHEMBL16798420 | 0.98 | ALOX15 (0.41) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| Hydrochloric Acid SCHEMBL8853649 | 0.98 | ALOX15 (0.41) | ALOX15ALDH1A1METAP2METAP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009706-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY | 2025-01-09 | — | — | US | claimed |
| US-12083089-B2 | Compositions and methods for stimulating ventilatory and/or respiratory drive | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-09-10 | — | — | US | claimed |
| EP-4373484-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-05-29 | — | — | EP | claimed |
| US-20240139140-A9 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | CASE WESTERN RESERVE UNIVERSITY | 2024-05-02 | — | — | US | claimed |
| WO-2023003810-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-01-26 | — | — | WO | claimed |
| CN-114316087-B | Hyaluronic acid cross-linking active material, preparation method and application thereof | 常州百瑞吉生物医药有限公司 | 2022-10-28 | — | — | CN | claimed |
| US-20220273604-A1 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | UNIV CASE WESTERN RESERVE (US) | 2022-09-01 | — | — | US | claimed |
| CN-114316087-A | Hyaluronic acid cross-linking active material, preparation method and application thereof | 常州百瑞吉生物医药有限公司 | 2022-04-12 | — | — | CN | claimed |
| US-10543187-B2 | Compositions and methods for stimulating ventilatory and/or respiratory drive | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-01-28 | — | — | US | claimed |
| US-20190231732-A1 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | CASE WESTERN UNIVERSITY | 2019-08-01 | — | — | US | claimed |
| WO-2015085003-A1 | COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION | IMMUNOGEN, INC. (US) | 2015-06-11 | — | — | WO | claimed |
| US-8450089-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2013-05-28 | — | — | US | claimed |
| EP-2088140-B1 | DIHYDRAZIDE COMPOUNDS, PREPARATION AND USES THEREOF | BIOREGEN BIOMEDICAL CHANGZHOU (CN) | 2013-05-15 | — | — | EP | claimed |
| CN-102802605-A | Stable lipid formulations of apoptosis promoters | ABBOTT LAB | 2012-11-28 | — | — | CN | claimed |
| EP-2424499-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | Abbott Laboratories (US) | 2012-03-07 | — | — | EP | claimed |
| US-8067636-B2 | Dihydrazide compounds, preparation and uses thereof | BIOREGEN BIOMEDICAL (SHANGHAI) CO., LTD (CN) | 2011-11-29 | — | — | US | claimed |
| WO-2010127193-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | WO | claimed |
| US-20100278905-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBVIE INC. | 2010-11-04 | — | — | US | claimed |
| US-20100048952-A1 | DIHYDRAZIDE COMPOUNDS, PREPARATION AND USES THEREOF | BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) | 2010-02-25 | — | — | US | claimed |
| EP-2088140-A1 | DIHYDRAZIDE COMPOUNDS, PREPARATION AND USES THEREOF | Bioregen Biomedical (Shanghai) Co., Ltd. (CN) | 2009-08-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190231732-A1 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | CHRM3, CTH, SLC18A3 | ALOX15 1262/4885ALDH1A1 3974/4885METAP2 1138/4885 |
| US-12083089-B2 | Compositions and methods for stimulating ventilatory and/or respiratory drive | OPRM1, OPRK1, OPRD1 | ALOX15 1043/4885ALDH1A1 2591/4885METAP2 1728/4885 |
| US-20100048952-A1 | DIHYDRAZIDE COMPOUNDS, PREPARATION AND USES THEREOF | GRHPR, HRH4, HRH2 | ALOX15 3823/4885ALDH1A1 47/4885METAP2 4547/4885 |
| US-20220273604-A1 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | OPRM1, OPRK1, OPRD1 | ALOX15 1043/4885ALDH1A1 2591/4885METAP2 1728/4885 |
| US-10543187-B2 | Compositions and methods for stimulating ventilatory and/or respiratory drive | CHRM3, CTH, SLC18A3 | ALOX15 1262/4885ALDH1A1 3974/4885METAP2 1138/4885 |
| US-20100278905-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | BCL2, BAX, BCOR | ALOX15 615/4885ALDH1A1 3985/4885METAP2 4253/4885 |
| US-20250009706-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | OPRM1, OPRK1, OPRD1 | ALOX15 1219/4885ALDH1A1 630/4885METAP2 427/4885 |
| US-20240139140-A9 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | OPRM1, OPRK1, OPRD1 | ALOX15 1043/4885ALDH1A1 2591/4885METAP2 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.