Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034337 | 0.75 | HPGD (0.52) | HPGDMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9409748 | 0.74 | CUL4A (0.37) | HPGDMAPTKMT2AMEN1PKM | |
| SCHEMBL3418797 | 0.71 | POLB (0.40) | MAPTKMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL27703251 | 0.70 | POLB (0.39) | HPGDMAPTPKMTSHRSMN1; SMN2 | |
| SCHEMBL5102722 | 0.70 | KCNA5 (0.63) | HPGDPKMHTTSMN1; SMN2NPC1 | |
| SCHEMBL28341914 | 0.69 | KMT2A (0.40) | HPGDMAPTKMT2APKMHTT | |
| SCHEMBL5949707 | 0.66 | EPHX1 (0.48) | HPGDPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL25854787 | 0.65 | ANPEP (0.42) | HPGDPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22412349 | 0.64 | MGLL (0.69) | MAPTKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL27823605 | 0.64 | FAAH (0.53) | HPGDMAPTKMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349846-B1 | ARYLATED FURANE AND THIOPHENE CARBOXYLIC ACID AMIDES WITH POTASSIUM CHANNEL BLOCKING EFFECT | AVENTIS PHARMA GMBH (DE) | 2005-02-09 | — | — | EP | disclosed |
| EP-1349846-A1 | ARYLATED FURANE AND THIOPHENE CARBOXYLIC ACID AMIDES WITH POTASSIUM CHANNEL BLOCKING EFFECT | Aventis Pharma Deutschland GmbH (DE) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002048131-A1 | ARYLATED FURANE AND THIOPHENE CARBOXYLIC ACID AMIDES WITH POTASSIUM CHANNEL BLOCKING EFFECT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-20 | — | — | WO | disclosed |