SCHEMBL616172

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL616488	0.86	PTGS2 (0.49)	PTGS2PDGFRBPDGFRAHTTMAPT
	SCHEMBL618661	0.83	TUBB4A (0.44)	PDGFRBTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL617918	0.83	ALDH1A1 (0.39)	HTTMAPTLMNATUBB4ATUBB
	SCHEMBL618668	0.82	CHEK1 (0.39)	HTTMAPTLMNATUBB4ATUBB
	SCHEMBL618306	0.82	SLC10A2 (0.42)	PDGFRBPDGFRAMAPTTUBB4ATUBB
	SCHEMBL618380	0.82	EPHB4 (0.41)	PDGFRBHTTMAPTLMNANPSR1
	SCHEMBL618171	0.80	TUBB4A (0.45)	HTTMAPTLMNATUBB4ATUBB
	SCHEMBL618942	0.80	TUBB4A (0.40)	PDGFRBTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL16471449	0.80	ADORA1 (0.33)	HTTMAPTLMNATUBB4ATUBB
	SCHEMBL618811	0.80	MAPT (0.42)	PDGFRBPDGFRAHTTMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.