Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161924 | 1.00 | GSTP1 (0.38) | GSTP1ALDH1A1MAPTPAMPOLB | |
| SCHEMBL5250269 | 0.85 | ABCB1 (0.42) | GSTP1ALDH1A1MAPTPAMCACNA1B | |
| SCHEMBL6063753 | 0.84 | ELANE (0.36) | ALDH1A1MDM2 | |
| SCHEMBL6063582 | 0.84 | ELANE (0.36) | ALDH1A1MDM2 | |
| SCHEMBL22636048 | 0.75 | ELANE (0.35) | ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL6918361 | 0.75 | ELANE (0.35) | ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL6835149 | 0.73 | LMNA (0.34) | MDM2 | |
| SCHEMBL7063555 | 0.73 | MAPT (0.32) | ALDH1A1MAPTPOLBMDM2 | |
| SCHEMBL7262995 | 0.71 | SIGMAR1 (0.35) | MDM2MAOB | |
| SCHEMBL8990837 | 0.71 | MDM2 (0.42) | ALDH1A1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |