Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262995 | 0.87 | SIGMAR1 (0.35) | LMNACYP1A2CYP2C9CYP2C19RECQL | |
| SCHEMBL9236157 | 0.78 | MGAM (0.34) | LMNACYP1A2CYP2C9CYP2C19RECQL | |
| SCHEMBL6835179 | 0.77 | NPSR1 (0.33) | NPSR1MDM2PTGDR2 | |
| SCHEMBL6063582 | 0.76 | ELANE (0.36) | SMN1; SMN2NPSR1MDM2 | |
| SCHEMBL6063753 | 0.76 | ELANE (0.36) | SMN1; SMN2NPSR1MDM2 | |
| SCHEMBL7898908 | 0.76 | MDM2 (0.34) | MDM2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7898909 | 0.76 | S1PR3 (0.39) | — | |
| SCHEMBL8990837 | 0.75 | MDM2 (0.42) | LMNASMN1; SMN2MDM2 | |
| SCHEMBL22636048 | 0.75 | ELANE (0.35) | SMN1; SMN2NPSR1PTGDR2 | |
| SCHEMBL6918361 | 0.75 | ELANE (0.35) | SMN1; SMN2NPSR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040191926-A1 | Ptp1b inhibitors and ligands | NATIONAL INSTITUTES OF HEALTH | 2004-09-30 | — | — | US | disclosed |