Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162428 | 1.00 | EGLN1 (0.45) | EGLN1HCRTR1HCRTR2FFAR4GRN | |
| SCHEMBL6164463 | 0.91 | EGLN1 (0.44) | EGLN1HCRTR1HCRTR2P2RX3 | |
| SCHEMBL6164470 | 0.91 | EGLN1 (0.44) | EGLN1HCRTR1HCRTR2P2RX3 | |
| SCHEMBL6161464 | 0.86 | HCRTR1 (0.36) | EGLN1HCRTR1HCRTR2P2RX3ACACB | |
| SCHEMBL6161473 | 0.86 | HCRTR1 (0.36) | EGLN1HCRTR1HCRTR2P2RX3ACACB | |
| SCHEMBL6162057 | 0.79 | S1PR5 (0.46) | — | |
| SCHEMBL6157819 | 0.79 | KMT2A (0.44) | EGLN1 | |
| SCHEMBL6158889 | 0.75 | EGLN1 (0.51) | EGLN1HCRTR1HCRTR2GRNSORT1 | |
| SCHEMBL6159553 | 0.74 | EGLN1 (0.49) | EGLN1HCRTR1HCRTR2GRNSORT1 | |
| SCHEMBL3593084 | 0.73 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165064-A1 | Novel thiol derivative, process for producing the same and use thereof | TAKEDA PHARMACEUTICALS NORTH AMERICA, INC. | 2005-07-28 | — | — | US | disclosed |
| EP-1500658-A1 | NOVEL THIOL DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165064-A1 | Novel thiol derivative, process for producing the same and use thereof | TST, QSOX1, MMP1 | EGLN1 841/4885HCRTR1 2881/4885HCRTR2 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.