Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.37 |
| ▸ | FEN1 | P39748 | 7/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166329 | 0.92 | ALOX5 (0.35) | ALOX5TLR8TLR7MAPTMAPK1 | |
| SCHEMBL6165012 | 0.83 | ALOX5 (0.42) | ALOX5TLR8TLR7MAPTMAPK1 | |
| SCHEMBL6165006 | 0.81 | ALOX5 (0.43) | ALOX5TLR8TLR7MAPTMAPK1 | |
| SCHEMBL6162975 | 0.79 | MAPK14 (0.44) | ALOX5TLR8TLR7MAPTMAPK1 | |
| SCHEMBL7108632 | 0.78 | RXFP1 (0.39) | ALOX5APFEN1TLR8TLR7MMP3 | |
| SCHEMBL6166441 | 0.78 | MMP2 (0.42) | ALOX5TLR8TLR7MAPTMAPK1 | |
| SCHEMBL6163317 | 0.75 | MAPT (0.56) | ALOX5MAPTMAPK1SETD7SMN1; SMN2 | |
| SCHEMBL6162430 | 0.75 | SMN1; SMN2 (0.60) | ALOX5MAPTMAPK1SETD7SMN1; SMN2 | |
| SCHEMBL6167436 | 0.73 | USP30 (0.55) | USP30 | |
| SCHEMBL5885775 | 0.72 | USP30 (0.37) | ALOX5APFEN1MAPTMMP3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |