Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166050 | 0.78 | HTT (0.47) | HTT | |
| SCHEMBL6164169 | 0.76 | HTT (0.48) | HTT | |
| SCHEMBL6166822 | 0.75 | HTT (0.44) | HTT | |
| SCHEMBL6167339 | 0.73 | HTT (0.45) | HTT | |
| SCHEMBL6164255 | 0.72 | HTT (0.46) | HTT | |
| SCHEMBL6162358 | 0.72 | HTT (0.46) | HTT | |
| SCHEMBL6164630 | 0.69 | HTT (0.41) | HTT | |
| SCHEMBL6164796 | 0.68 | HTT (0.43) | HTT | |
| SCHEMBL6166773 | 0.67 | HTT (0.52) | HTT | |
| SCHEMBL6166242 | 0.63 | HTT (0.42) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177185-B1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-04-20 | — | — | EP | disclosed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |