Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316449 | 0.79 | MAPT (0.39) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL14723169 | 0.79 | MEN1 (0.49) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL7922229 | 0.79 | MEN1 (0.44) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL539263 | 0.79 | PARP1 (0.41) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL1144726 | 0.79 | MEN1 (0.44) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL29804933 | 0.79 | MEN1 (0.44) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL6956986 | 0.78 | MAPT (0.46) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL19141612 | 0.75 | PNP (0.39) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL30477591 | 0.75 | CTSS (0.38) | MAPTPNPMEN1KMT2AALDH1A1 | |
| SCHEMBL12277149 | 0.75 | MAPT (0.36) | MAPTPNPMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143247-A1 | LINKER FOR CHARACTERIZING SEQUENCING OF TARGET POLYNUCLEOTIDE, CONSTRUCT, METHOD, AND USE | 成都齐碳科技有限公司 | 2023-08-03 | — | — | WO | claimed |
| CN-114457145-A | Linkers, constructs, methods, and uses for characterizing sequencing of target polynucleotides | 成都齐碳科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-20260137697-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIV DE MONTREAL (CA) | 2026-05-21 | — | — | US | disclosed |
| CN-122036621-A | Fluorine substituted benzimidazolyl aniline compound and synthetic method and application thereof | 中茂绿能科技(西安)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| WO-2026090491-A1 | ENHANCED DELIVERY OF DISEASE-TARGETED NANOBODY-SIRNA CONJUGATES | OHIO STATE INNOVATION FOUNDATION (US) | 2026-04-30 | — | — | WO | disclosed |
| US-12559766-B2 | Peanut with reduced allergen levels | INGATEYGEN LLC (US) | 2026-02-24 | — | — | US | disclosed |
| US-12404274-B2 | Macrocycles as factor xia inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-09-02 | — | — | US | disclosed |
| EP-4602047-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | The Universite de Montreal (CA) | 2025-08-20 | — | — | EP | disclosed |
| EP-3327140-B1 | CAPTURE PROBES IMMOBILIZABLE VIA L-NUCLEOTIDE TAIL | GEN PROBE INC (US) | 2025-08-06 | — | — | EP | disclosed |
| CN-120035595-A | Thiazolo [5,4-d ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2025-05-23 | — | — | CN | disclosed |
| US-20250136658-A1 | ANTICONVULSANT AND NEUROPROTECTIVE AGENT | THE UAB RESEARCH FOUNDATION | 2025-05-01 | — | — | US | disclosed |
| US-20120041190-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-02-16 | — | — | US | disclosed |
| WO-2011100401-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-08-18 | — | — | WO | disclosed |
| EP-2069536-A1 | METHODS OF NONSPECIFIC TARGET CAPTURE OF NUCLEIC ACIDS | Gen-Probe Incorporated (US) | 2009-06-17 | — | — | EP | disclosed |
| US-7504513-B2 | Thiazolyl-benzimidazoles | HOFFMAN-LA ROCHE INC. (US) | 2009-03-17 | — | — | US | disclosed |
| US-7504513-B2 | Thiazolyl-benzimidazoles | HOFFMAN-LA ROCHE INC. (US) | 2009-03-17 | — | — | US | disclosed |
| US-20080286775-A1 | METHODS OF NONSPECIFIC TARGET CAPTURE OF NUCLEIC ACIDS | GEN-PROBE INCORPORATED (US) | 2008-11-20 | — | — | US | disclosed |
| WO-2008016988-A1 | METHODS OF NONSPECIFIC TARGET CAPTURE OF NUCLEIC ACIDS | GEN-PROBE INCORPORATED (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20070203210-A1 | Thiazolyl-benzimidazoles | BOYLAN JOHN FREDERICK | 2007-08-30 | — | — | US | disclosed |
| US-20070203210-A1 | Thiazolyl-benzimidazoles | BOYLAN JOHN FREDERICK | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041190-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | MAPT 326/4885PNP 4526/4885MEN1 376/4885 |
| US-12404274-B2 | Macrocycles as factor xia inhibitors | TFPI, TFPI2, F11 | MAPT 326/4885PNP 4526/4885MEN1 376/4885 |
| US-20070203210-A1 | Thiazolyl-benzimidazoles | CYP3A7, CYP2C19, CYP3A5 | MAPT 1573/4885PNP 1418/4885MEN1 557/4885 |
| US-12559766-B2 | Peanut with reduced allergen levels | H1-2, CPA2, RNASEH1 | MAPT 2600/4885PNP 1667/4885MEN1 4877/4885 |
| US-20260137697-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NRAS, KRAS, BRAF | MAPT 4264/4885PNP 2000/4885MEN1 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.