Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062909 | 0.98 | HPGDS (0.58) | HPGDSHTTUSP30GPR119PRMT5 | |
| SCHEMBL6168833 | 0.89 | HTT (0.51) | HPGDSHTTGPR119PTPN2PTPN1 | |
| SCHEMBL2834170 | 0.89 | HPGDS (0.70) | HPGDSUSP30GPR119PRMT5KDM4E | |
| SCHEMBL27797117 | 0.88 | P2RY14 (0.53) | HPGDSHTTGPR119KDM4EMEN1 | |
| SCHEMBL27776225 | 0.87 | HPGDS (0.49) | HPGDSHTTUSP30GPR119KDM4E | |
| SCHEMBL310851 | 0.87 | SMN1; SMN2 (0.49) | HPGDSHTTUSP30KDM4E | |
| SCHEMBL6167825 | 0.86 | ALDH1A1 (0.54) | HTTPRMT5KDM4EMEN1ALDH1A1 | |
| SCHEMBL6167533 | 0.85 | HPGDS (0.41) | HPGDSHTTUSP30GPR119PRMT5 | |
| SCHEMBL2062893 | 0.85 | GPR119 (0.51) | HPGDSHTTGPR119PTPN2PTPN1 | |
| SCHEMBL311477 | 0.85 | HPGDS (0.48) | HPGDSHTTGPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |
| US-20040077640-A1 | Sodium channel modulators derived from 2-piperidylimidazoles | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077640-A1 | Sodium channel modulators derived from 2-piperidylimidazoles | KCNH1, HCN4, KCNH2 | HPGDS 3832/4885HTT 4159/4885USP30 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.