Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168199 | 0.90 | HTR2B (0.38) | HPGDSHTR2BHTTGPR119KDM4E | |
| SCHEMBL6168913 | 0.86 | KDM4E (0.41) | HTR2BPRMT5KDM4EALDH1A1HPGD | |
| SCHEMBL6167211 | 0.85 | HPGDS (0.56) | HPGDSHTTUSP30PRMT5GPR119 | |
| SCHEMBL2062909 | 0.83 | HPGDS (0.58) | HPGDSHTTUSP30PRMT5GPR119 | |
| SCHEMBL6167911 | 0.82 | L3MBTL1 (0.37) | HTR2BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27507420 | 0.80 | HTR2B (0.40) | HPGDSHTR2BHTTKDM4EALDH1A1 | |
| SCHEMBL6168951 | 0.78 | HTR2B (0.51) | HTR2BACACB | |
| SCHEMBL6167825 | 0.76 | ALDH1A1 (0.54) | HTR2BHTTPRMT5KDM4EMEN1 | |
| SCHEMBL2834170 | 0.75 | HPGDS (0.70) | HPGDSHTR2BUSP30PRMT5GPR119 | |
| SCHEMBL6167913 | 0.75 | TRPC6 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |