Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30278666 | 0.79 | TRPA1 (0.42) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL13233212 | 0.78 | SIGMAR1 (0.47) | TRPA1SIGMAR1CYP1A2EPHX1ALPI | |
| SCHEMBL27081824 | 0.76 | CACNA2D1 (0.49) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL10621350 | 0.76 | CA1 (0.53) | — | |
| SCHEMBL10621344 | 0.76 | CA1 (0.53) | — | |
| SCHEMBL131351 | 0.75 | SLC6A2 (0.54) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL28422388 | 0.75 | TAAR1 (0.43) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL9794416 | 0.75 | CPA1 (0.40) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL108646 | 0.74 | TRPA1 (0.58) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL5561126 | 0.74 | CYP1A2 (0.50) | TRPA1CYP1A2EPHX1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943722-B1 | PROTECTIVE COATING FOR LED LAMP | CREE INC (US) | 2019-08-28 | — | — | EP | disclosed |
| US-10093633-B2 | Functionalized 4- and 5-vinyl substituted regioisomers of 1, 2, 3-triazoles via 1, 3-dipolar cycloaddition and polymers thereof | ISP INVESTMENTS LLC (US) | 2018-10-09 | — | — | US | disclosed |
| EP-2405757-B1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-9570661-B2 | Protective coating for LED lamp | CREE, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160083356-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3- DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2016-03-24 | — | — | US | disclosed |
| EP-2943722-A1 | PROTECTIVE COATING FOR LED LAMP | Cree, Inc. (US) | 2015-11-18 | — | — | EP | disclosed |
| US-8993698-B2 | 4- and 5 substituted 1,2,3-triazole moieties with at least one remote polymerizable moiety and polymers thereof | ISP INVESTMENTS INC. (US) | 2015-03-31 | — | — | US | disclosed |
| WO-2014110211-A1 | PROTECTIVE COATING FOR LED LAMP | CREE, INC. (US) | 2014-07-17 | — | — | WO | disclosed |
| US-20140191648-A1 | PROTECTIVE COATING FOR LED LAMP | CREE, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20120142846-A1 | 4- AND 5 SUBSTITUTED 1,2,3-TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | AVOCA LLC | 2012-06-07 | — | — | US | disclosed |
| EP-2451286-A1 | 4- AND 5 SUBSTITUTED 1,2,3- TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | Isp Investments Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| US-20120041040-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2012-02-16 | — | — | US | disclosed |
| EP-2405757-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | Isp Investments Inc. (US) | 2012-01-18 | — | — | EP | disclosed |
| WO-2011005806-A1 | 4- AND 5 SUBSTITUTED 1,2,3- TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010104837-A1 | FUNCTIONALIZED 4-AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-4983627-A | Treating atherosclerosis, thrombosis and vasospasms; anticholesterol,-secretory,-ulcer and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1991-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041040-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ADH5, ADH1A, ADH1C | TRPA1 1898/4885TAAR1 18/4885SLC6A2 3534/4885 |
| US-10093633-B2 | Functionalized 4- and 5-vinyl substituted regioisomers of 1, 2, 3-triazoles via 1, 3-dipolar cycloaddition and polymers thereof | ADH5, ADH1A, ADH1C | TRPA1 1898/4885TAAR1 18/4885SLC6A2 3534/4885 |
| US-20120142846-A1 | 4- AND 5 SUBSTITUTED 1,2,3-TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | H1-4, NPY4R, RXFP4 | TRPA1 3643/4885TAAR1 711/4885SLC6A2 4129/4885 |
| US-20160083356-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3- DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ADH5, ADH1A, ADH1C | TRPA1 1898/4885TAAR1 18/4885SLC6A2 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.