Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169897 | 0.85 | SIRT1 (0.55) | L3MBTL1MAPTKMT2AMEN1SIRT1 | |
| SCHEMBL6167361 | 0.84 | GAA (0.58) | MAPTKMT2AMEN1LMNAADORA3 | |
| SCHEMBL26948702 | 0.77 | LMNA (0.64) | L3MBTL1MAPTLMNAADORA3GAA | |
| SCHEMBL1597896 | 0.76 | GAA (0.70) | L3MBTL1MAPTKMT2AMEN1GAA | |
| SCHEMBL6169375 | 0.72 | GAA (0.50) | L3MBTL1MAPTKMT2AMEN1LMNA | |
| SCHEMBL19420143 | 0.72 | GAA (0.62) | L3MBTL1MAPTKMT2AMEN1GAA | |
| SCHEMBL11017764 | 0.71 | LMNA (0.73) | MAPTKMT2ALMNAADORA3GAA | |
| SCHEMBL6167967 | 0.70 | ALDH1A1 (0.52) | L3MBTL1MAPTKMT2AMEN1GAA | |
| SCHEMBL26948696 | 0.70 | LMNA (0.46) | L3MBTL1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1597383 | 0.69 | MAPT (0.50) | L3MBTL1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |