Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167967 | 0.84 | ALDH1A1 (0.52) | GAACYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL6167361 | 0.79 | GAA (0.58) | GAACYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL13879419 | 0.75 | AR (0.62) | GAACYP3A4CYP2C19ALDH1A1MAPT | |
| SCHEMBL9638554 | 0.73 | GAA (0.84) | GAACYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL5955265 | 0.73 | MEN1 (0.54) | GAACYP3A4ALDH1A1SMOLMNA | |
| SCHEMBL5954448 | 0.72 | SMO (0.56) | GAAALDH1A1MAPTRAB9ASMO | |
| SCHEMBL6169513 | 0.72 | L3MBTL1 (0.48) | GAACYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL6169699 | 0.72 | GAA (0.49) | GAACYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL6626137 | 0.72 | MAPT (0.50) | GAACYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL9638535 | 0.71 | GAA (0.84) | GAACYP1A2CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |