Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170794 | 0.90 | PLA2G2A (0.44) | RAB9AMAPTPPARGPPARAPLA2G2A | |
| SCHEMBL8510685 | 0.86 | PLA2G2A (0.51) | MAPTPLA2G2AMAPK8KDM4EALDH1A1 | |
| SCHEMBL9899016 | 0.81 | NR4A2 (0.50) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL1009498 | 0.81 | TSHR (0.48) | MAPTMAPK8KDM4EALDH1A1KMT2A | |
| SCHEMBL17733151 | 0.80 | ALDH1A1 (0.49) | MAPTPPARGKDM4EALDH1A1KMT2A | |
| SCHEMBL9899615 | 0.80 | PLA2G2A (0.49) | MAPTPLA2G2AMAPK8KDM4EALDH1A1 | |
| SCHEMBL3151462 | 0.79 | MAPK8 (0.47) | MAPK8ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6383895 | 0.79 | BACE1 (0.51) | MAPTPLA2G2AKDM4EALDH1A1HPGD | |
| SCHEMBL9899201 | 0.79 | NR4A2 (0.46) | MAPTMAPK8KDM4EALDH1A1KMT2A | |
| SCHEMBL31435276 | 0.78 | KDM4E (0.46) | RAB9AMAPTKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112263-B1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1112263-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6113814-A | PHOTOCHROMIC; END-CAPPED WITH A POLYMERIZABLE GROUP. | TRANSITIONS OPTICAL, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| WO-2000015629-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | disclosed |