Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510685 | 0.89 | PLA2G2A (0.51) | ALDH1A1HPGDKDM4ENPSR1MAPT | |
| SCHEMBL17736803 | 0.88 | KDM4E (0.52) | ALDH1A1HPGDKDM4ENPSR1KMT2A | |
| SCHEMBL24620800 | 0.87 | HTT (0.48) | ALDH1A1HPGDKDM4ENPSR1KMT2A | |
| SCHEMBL9899615 | 0.82 | PLA2G2A (0.49) | ALDH1A1HPGDKDM4ETDP1MAPT | |
| SCHEMBL6383895 | 0.82 | BACE1 (0.51) | ALDH1A1HPGDKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL15247977 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4ENPSR1KMT2A | |
| SCHEMBL6169984 | 0.80 | RAB9A (0.40) | ALDH1A1HPGDKDM4ENPSR1KMT2A | |
| SCHEMBL16301294 | 0.79 | DGAT1 (0.46) | ALDH1A1HPGDKDM4EKMT2ATDP1 | |
| SCHEMBL15452335 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4ENPSR1KMT2A | |
| SCHEMBL25876669 | 0.78 | BACE1 (0.44) | ALDH1A1HPGDKDM4ENPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643905-B2 | Phenylnaphthol derivatives | TOKUYAMA CORPORATION (JP) | 2017-05-09 | — | — | US | disclosed |
| US-20160130203-A1 | NOVEL PHENYLNAPHTHOL DERIVATIVES | TOKUYAMA CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| EP-3018115-A1 | NOVEL PHENYL NAPTHOL DERIVATIVE | Tokuyama Corporation (JP) | 2016-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130203-A1 | NOVEL PHENYLNAPHTHOL DERIVATIVES | AHR, ARL1, PAH | ALDH1A1 889/4885HPGD 1570/4885KDM4E 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.