Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172100 | 0.90 | LMNA (0.38) | LMNAFNTAFNTBPGGT1BABL1 | |
| SCHEMBL6173731 | 0.87 | KDM4E (0.35) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6172120 | 0.86 | KDM4E (0.35) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6174750 | 0.85 | LMNA (0.39) | LMNACXCR3NPBWR1MCHR1POLB | |
| SCHEMBL6173698 | 0.84 | LMNA (0.42) | LMNACXCR3NPBWR1MCHR1POLB | |
| SCHEMBL6175153 | 0.82 | LIPE (0.43) | ABL1POLB | |
| SCHEMBL6174788 | 0.81 | LMNA (0.38) | LMNAGRIN2BABL1NPBWR1MCHR1 | |
| SCHEMBL6173186 | 0.79 | LMNA (0.40) | LMNACXCR3NPBWR1MCHR1POLB | |
| SCHEMBL6172442 | 0.78 | LMNA (0.40) | LMNACXCR3NPBWR1MCHR1POLB | |
| SCHEMBL6170501 | 0.78 | LMNA (0.42) | LMNACXCR3POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |