Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGLRA1GLRBKCNK10KCNK18KCNK2KCNK3KCNK9
The experimentally established mechanism targets of Enflurane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enflurane SCHEMBL4056349 | 1.00 | MEN1 (0.39) | MEN1KMT2A | |
| Enflurane SCHEMBL8940191 | 0.87 | ALDH1A1 (0.52) | MEN1KMT2A | |
| Enflurane SCHEMBL13723343 | 0.83 | TSHR (0.35) | MEN1KMT2A | |
| SCHEMBL11419898 | 0.81 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL10804047 | 0.81 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL10801368 | 0.81 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8646180 | 0.77 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL11617110 | 0.77 | MEN1 (0.36) | MEN1KMT2A | |
| Enflurane SCHEMBL8667071 | 0.77 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL9154522 | 0.73 | MEN1 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6785 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719552-A1 | INDUCTION OF GENERAL ANESTHESIA IN ADULTS UNDERGOING ELECTIVE SURGERY | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| US-12594388-B2 | Device to deliver a predetermined amount of a substance to a natural orifice of the body | APTARGROUP, INC. (US) | 2026-04-07 | — | — | US | claimed |
| EP-4157407-B1 | INHALER DEVICE FOR INHALABLE LIQUIDS | MEDICAL DEVELOPMENTS INTERNATIONAL LTD (AU) | 2026-03-25 | — | — | EP | claimed |
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| US-20260048034-A1 | COMPOSITIONS AND METHODS FOR ENHANCING THE EFFICACY OF DICARBOXYLIC ACID ESTERS, AND USES THEREOF | NEW FRONTIER LABS LLC (US) | 2026-02-19 | — | — | US | claimed |
| EP-4696307-A1 | COMPOSITIONS AND METHODS FOR ENHANCING THE EFFICACY OF DICARBOXYLIC ACID ESTERS, AND USES THEREOF | New Frontier Labs, LLC (US) | 2026-02-18 | — | — | EP | claimed |
| EP-4293681-B1 | SYSTEMS AND METHODS FOR MANAGING AIR QUALITY IN A SURGICAL ENVIRONMENT | STRYKER CORP (US) | 2025-12-10 | — | — | EP | claimed |
| US-20250242092-A1 | SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS | SIO2 MEDICAL PRODUCTS INC (US) | 2025-07-31 | — | — | US | claimed |
| US-20250235641-A1 | DEVICE TO DELIVER A PREDETERMINED AMOUNT OF A SUBSTANCE TO A NATURAL ORIFICE OF THE BODY | APTARGROUP INC. (US) | 2025-07-24 | — | — | US | claimed |
| US-20250216369-A1 | Gas Detection, Identification, and Quantification Systems and Devices for Medical Applications | BECTON, DICKINSON AND COMPANY | 2025-07-03 | — | — | US | claimed |
| EP-0247789-A2 | Gas constituent measurement and recording | The BOC Group, Inc. (US) | 1987-12-02 | — | — | EP | claimed |
| CN-86208478-U | ANAESTHETIC PROCESS MONITOR | — | 1987-11-18 | — | — | CN | claimed |
| EP-0100788-B1 | PROCESS FOR PREPARING 1,1,2-TRIFLUORO-2-CHLOROETHYL DIFLUOROMETHYL ETHER | Daikin Kogyo Co., Ltd. (JP) | 1987-06-10 | — | — | EP | claimed |
| US-4622219-A | Method of inducing local anesthesia using microdroplets of a general anesthetic | RTP PHARMA INC. (CA) | 1986-11-11 | — | — | US | claimed |
| US-4504686-A | Process for preparing 1,1,2-trifluoro-2-chloroethyl difluoromethyl ether | DAIKIN KOGYO CO., LTD. (JP) | 1985-03-12 | — | — | US | claimed |
| US-4455378-A | Method of determining the content of an anesthetic gas in a selected location | DRAGERWERK AKTIENGESELLSCHAFT (DE) | 1984-06-19 | — | — | US | claimed |
| EP-0100788-A1 | Process for preparing 1,1,2-trifluoro-2-chloroethyl difluoromethyl ether | Daikin Kogyo Co., Ltd. (JP) | 1984-02-22 | — | — | EP | claimed |
| US-4334105-A | Method for the dehalogenation of ethers | AIRCO, INC. (US) | 1982-06-08 | — | — | US | claimed |
| US-4233842-A | Apparatus for measurement of expiration fluids | UNIVERSITY OF UTAH (US) | 1980-11-18 | — | — | US | claimed |
| US-4015599-A | Anesthetic delivery system | ROHM AND HAAS COMPANY (US) | 1977-04-05 | — | — | US | claimed |