Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173367 | 0.82 | MAPT (0.48) | ALDH1A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL6170768 | 0.82 | TP53 (0.54) | ALDH1A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL6170577 | 0.81 | TP53 (0.45) | ALDH1A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL6171924 | 0.79 | ADORA2A (0.45) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL7470525 | 0.76 | ADORA2A (0.39) | MAPTTP53HSD17B10LMNAADORA2A | |
| SCHEMBL6170859 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL6612626 | 0.72 | ADORA2A (0.38) | ALDH1A1SMN1; SMN2TP53HPGDKDM4E | |
| SCHEMBL6612393 | 0.72 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2TP53HPGDTSHR | |
| SCHEMBL6171107 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL7016945 | 0.68 | PDE4A (0.52) | ALDH1A1SMN1; SMN2TP53HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263757-B1 | BENZTHIAZOLES AS TNF AND PDE-IV INHIBITORS | DARWIN DISCOVERY LTD (GB) | 2005-07-27 | — | — | EP | claimed |