Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 12/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169951 | 0.90 | TSPO (0.46) | TSPOTDP1MEN1KMT2ANPC1 | |
| SCHEMBL6170009 | 0.86 | EGLN1 (0.42) | — | |
| SCHEMBL7813546 | 0.80 | HDAC6 (0.41) | — | |
| SCHEMBL6170913 | 0.80 | KMO (0.48) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL6170872 | 0.78 | TDP1 (0.46) | TDP1NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL7199062 | 0.78 | SMN1; SMN2 (0.49) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL7811933 | 0.78 | EGLN1 (0.37) | NPC1ALDH1A1MAPTRAB9ATP53 | |
| SCHEMBL6170787 | 0.77 | DYRK1A (0.42) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL6170477 | 0.77 | HASPIN (0.42) | TDP1KMT2ANPC1ALDH1A1TSHR | |
| SCHEMBL7257558 | 0.76 | TSPO (0.45) | TSPOTDP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097138-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LAFON LABOR (FR) | 2005-12-07 | — | — | EP | disclosed |
| US-6593342-B1 | Activity on the proliferation of clonogenic cells in tumours and comprising an efficient amount of a compound selected among the compounds | LABORATOIRE L. LAFON (FR) | 2003-07-15 | — | — | US | disclosed |