Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CBX7 | O95931 | 1/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170009 | 0.80 | EGLN1 (0.42) | EGLN1 | |
| SCHEMBL7811936 | 0.80 | RAB9A (0.38) | EGLN1RAB9AKLK7KDM4ECYP3A4 | |
| SCHEMBL6170913 | 0.78 | KMO (0.48) | EGLN1RAB9AKLK7KDM4ECYP3A4 | |
| SCHEMBL6172328 | 0.78 | TSPO (0.54) | RAB9AKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL6169951 | 0.76 | TSPO (0.46) | EGLN1RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL6170787 | 0.76 | DYRK1A (0.42) | EGLN1RAB9AKLK7KDM4ECYP3A4 | |
| SCHEMBL6170872 | 0.75 | TDP1 (0.46) | RAB9AKLK7KDM4ECYP3A4HSD17B10 | |
| SCHEMBL7813546 | 0.74 | HDAC6 (0.41) | — | |
| SCHEMBL6168228 | 0.74 | KDM4E (0.46) | RAB9AKDM4ECYP3A4HSD17B10NPC1 | |
| SCHEMBL6170922 | 0.73 | ALDH1A1 (0.47) | RAB9AKLK7KDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097138-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2001-05-09 | — | — | EP | claimed |
| WO-2000003990-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | claimed |