Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173295 | 0.84 | USP30 (0.52) | USP30PPARGDGAT2HDAC4HDAC6 | |
| SCHEMBL25200353 | 0.79 | L3MBTL1 (0.53) | L3MBTL1MAPTMAPK1NTSR1NPSR1 | |
| SCHEMBL1775260 | 0.78 | HSD11B1 (0.59) | USP30L3MBTL1HSD11B1 | |
| SCHEMBL953899 | 0.78 | HSD11B1 (0.59) | USP30L3MBTL1HSD11B1 | |
| SCHEMBL1971844 | 0.78 | HSD11B1 (0.59) | USP30L3MBTL1HSD11B1 | |
| SCHEMBL7423685 | 0.78 | JMJD6 (0.45) | L3MBTL1MAPT | |
| SCHEMBL6162930 | 0.78 | HSD11B1 (0.58) | USP30PPARGNPSR1HSD11B1 | |
| SCHEMBL6174316 | 0.77 | KDM5A (0.54) | USP30PPARGMAPK11MAPK14HSD11B1 | |
| SCHEMBL951887 | 0.76 | HSD11B1 (0.65) | USP30L3MBTL1MAPTMAPK1NTSR1 | |
| SCHEMBL6944572 | 0.76 | HSD11B1 (0.65) | USP30L3MBTL1MAPTMAPK1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311501-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-11-02 | — | — | EP | disclosed |
| US-6924296-B2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040010017-A1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2004-01-15 | — | — | US | disclosed |
| EP-1311501-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014308-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010017-A1 | Antithrombotic agents | SERPINC1, TFPI, F11 | USP30 4295/4885PPARG 3664/4885DGAT2 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.