Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173722 | 0.92 | RAB9A (0.60) | RAB9ANPC1L3MBTL1MAPTLMNA | |
| SCHEMBL7887520 | 0.82 | DRD4 (0.60) | L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL15912908 | 0.80 | GPR119 (0.44) | RAB9AMAPTHTTALDH1A1 | |
| SCHEMBL3117217 | 0.78 | MAPT (0.52) | RAB9ANPC1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL735870 | 0.76 | MAPT (0.52) | RAB9ANPC1L3MBTL1MAPTHTT | |
| SCHEMBL16046663 | 0.75 | LTA4H (0.62) | RAB9ANPC1L3MBTL1MAPTHTT | |
| SCHEMBL8723261 | 0.75 | ACACB (0.41) | MAPTHTTALDH1A1LMNAKCNH2 | |
| SCHEMBL13202898 | 0.74 | RAB9A (0.67) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL335477 | 0.74 | LTA4H (0.64) | MAPTHTTALDH1A1LMNA | |
| SCHEMBL4673297 | 0.74 | MAPT (0.50) | RAB9ANPC1L3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261330-A1 | Derivatives of 2,2,4-trisubstituted tetrahydrofuran an antifungal agents | RANBAXY LABORATORIES LIMITED (IN) | 2005-11-24 | — | — | US | disclosed |
| EP-1497298-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087106-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261330-A1 | Derivatives of 2,2,4-trisubstituted tetrahydrofuran an antifungal agents | ERG28, DPM1, CYP51A1 | RAB9A 3748/4885NPC1 94/4885L3MBTL1 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.