Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227198 | 0.85 | CDYL (0.52) | TDP1ATML3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL13496176 | 0.82 | CYP4F2 (0.45) | TDP1ATML3MBTL1SIGMAR1CYP1A2 | |
| SCHEMBL21530481 | 0.81 | CYP1A2 (0.49) | TDP1ATML3MBTL1SIGMAR1MAPK8 | |
| SCHEMBL706704 | 0.79 | CTBP2 (0.46) | SIGMAR1KMT2ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6175375 | 0.78 | KMT2A (0.44) | TDP1L3MBTL1KMT2ACYP1A2KDM4E | |
| SCHEMBL20955519 | 0.78 | CYP1A2 (0.51) | L3MBTL1MAPK8MAPK9MAPK10CYP1A2 | |
| SCHEMBL1515893 | 0.78 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL13032640 | 0.78 | TAAR1 (0.43) | TDP1SIGMAR1MAPK8KMT2ACYP1A2 | |
| SCHEMBL1668464 | 0.78 | ALDH1A1 (0.45) | ATML3MBTL1KMT2APOLBKDM4E | |
| SCHEMBL28832891 | 0.78 | CYP2D6 (0.46) | SIGMAR1KMT2ACYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479806-B | D-amino acid oxidase inhibitors and therapeutic uses thereof | 心悦生医股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-22 | — | — | US | disclosed |
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-22 | — | — | US | disclosed |
| CN-111479806-A | D-amino acid oxidase inhibitors and therapeutic uses thereof | 心悦生医股份有限公司 | 2020-07-31 | — | — | CN | disclosed |
| US-20190337889-A1 | COMPOSITIONS AND METHODS OF REGULATING CANCER RELATED DISORDERS AND DISEASES | ONCO THERAPIES LLC (US) | 2019-11-07 | — | — | US | disclosed |
| WO-2019076329-A9 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-08-15 | — | — | WO | disclosed |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-07-02 | — | — | US | disclosed |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-07-02 | — | — | US | disclosed |
| WO-2019076329-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-04-25 | — | — | WO | disclosed |
| US-20190112289-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI, GUOCHUAN EMIL (US) | 2019-04-18 | — | — | US | disclosed |
| US-20190112289-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI, GUOCHUAN EMIL (US) | 2019-04-18 | — | — | US | disclosed |
| WO-2017070052-A1 | COMPOSITIONS AND METHODS OF REGULATING CANCER RELATED DISORDERS AND DISEASES | ONCO THERAPIES LLC (US) | 2017-04-27 | — | — | WO | disclosed |
| EP-1392280-A4 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| EP-1392280-A2 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | Abbott GmbH & Co. KG (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-20030096826-A1 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY | 2003-05-22 | — | — | US | disclosed |
| WO-2002089749-A2 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | ABBOTT GMBH & CO.KG (DE) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | DAO, DDO, DDC | TDP1 1911/4885ATM 3674/4885L3MBTL1 1508/4885 |
| US-20030096826-A1 | Arylsulfonamide ethers, and methods of use thereof | CASP1, IRAK1, STS | TDP1 1116/4885ATM 2414/4885L3MBTL1 2397/4885 |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | DAO, DDO, DDC | TDP1 1911/4885ATM 3674/4885L3MBTL1 1508/4885 |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | DAO, DDO, DDC | TDP1 1911/4885ATM 3674/4885L3MBTL1 1508/4885 |
| US-20190112289-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | DAO, DDO, DDC | TDP1 2080/4885ATM 3712/4885L3MBTL1 1460/4885 |
| US-20190337889-A1 | COMPOSITIONS AND METHODS OF REGULATING CANCER RELATED DISORDERS AND DISEASES | BRCA1, VHL, TP53 | TDP1 1324/4885ATM 905/4885L3MBTL1 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.