Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | GHSR | Q92847 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30892351 | 1.00 | ALDH3A1 (0.58) | ALDH3A1ALDH1A1ALDH2HTR1ADRD3 | |
| SCHEMBL6177786 | 0.92 | ALDH1A1 (0.55) | ALDH3A1ALDH1A1ALDH2HTR1ADRD3 | |
| SCHEMBL16048101 | 0.84 | ALDH3A1 (0.65) | ALDH3A1ALDH1A1ALDH2PARK7CHRM5 | |
| SCHEMBL6176074 | 0.83 | ALDH1A1 (0.58) | ALDH3A1ALDH1A1ALDH2PARK7 | |
| SCHEMBL10679908 | 0.83 | ALDH3A1 (0.58) | ALDH3A1ALDH1A1ALDH2GABRA1GABRG2 | |
| SCHEMBL16046979 | 0.81 | ALDH1A1 (0.62) | ALDH3A1ALDH1A1ALDH2PARK7 | |
| SCHEMBL29220078 | 0.81 | ALDH3A1 (0.65) | ALDH3A1ALDH1A1ALDH2PARK7CHRM5 | |
| SCHEMBL6275037 | 0.81 | PARK7 (0.66) | ALDH3A1ALDH1A1ALDH2PARK7 | |
| SCHEMBL32677715 | 0.81 | PARK7 (0.66) | ALDH3A1ALDH1A1ALDH2PARK7 | |
| SCHEMBL16366714 | 0.80 | ALDH1A1 (0.64) | ALDH3A1ALDH1A1ALDH2GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945979-A | Isatin derivative, preparation method thereof and application thereof in preparation of plant antibacterial drugs | 陕西师范大学 | 2024-04-30 | — | — | CN | disclosed |
| EP-1105376-B1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMA (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6576656-B1 | Such as 1-(2-diethylaminoethyl)-4-trifluoromethyl-6-carbamoyl-3-hydroxy-3-(2 -chlorophenyl)oxindole; growth hormone releaser | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1105376-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010975-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-03-02 | — | — | WO | disclosed |