Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178670 | 0.85 | ALDH1A1 (0.57) | AKR1C3AKR1C2MAPTMAPK1ALDH1A1 | |
| SCHEMBL30108026 | 0.84 | AKR1C3 (0.51) | AKR1C3AKR1C2MAPTMAPK1ALDH1A1 | |
| SCHEMBL6178609 | 0.82 | KCNMA1 (0.49) | GAAMAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL6178230 | 0.82 | L3MBTL1 (0.60) | MAPTMAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL17683159 | 0.80 | AKR1C3 (0.50) | GAAAKR1C3AKR1C2MAPTMAPK1 | |
| SCHEMBL30459933 | 0.80 | AKR1C3 (0.50) | GAAAKR1C3AKR1C2MAPTMAPK1 | |
| SCHEMBL6180141 | 0.79 | AKR1C3 (0.54) | AKR1C3AKR1C2MAPTMAPK1ALDH1A1 | |
| SCHEMBL4575162 | 0.78 | AKR1C3 (0.70) | GAAAKR1C3AKR1C2MAPTMAPK1 | |
| SCHEMBL13326003 | 0.77 | GAA (0.94) | GAAMAPTMAPK1ALDH1A1NPC1 | |
| SCHEMBL6178936 | 0.76 | L3MBTL1 (0.53) | GAAMAPTMAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |