Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035119 | 0.71 | PPIA (0.42) | — | |
| SCHEMBL5310455 | 0.70 | TACR1 (0.47) | — | |
| SCHEMBL6589522 | 0.69 | CHRM2 (0.69) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL13592145 | 0.69 | CHRM2 (0.69) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL7972011 | 0.69 | SLC6A2 (0.37) | — | |
| SCHEMBL13592129 | 0.69 | CHRM2 (0.67) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL4619902 | 0.68 | KEAP1 (0.68) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL5119960 | 0.68 | CHRM2 (0.60) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL5948024 | 0.67 | KEAP1 (0.57) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL4076565 | 0.67 | KEAP1 (0.57) | CHRM3CHRM2CHRM1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583741-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories, Limited (IN) | 2005-10-12 | — | — | EP | claimed |
| WO-2004056767-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-07-08 | — | — | WO | claimed |
| EP-1583741-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories, Limited (IN) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004056767-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-07-08 | — | — | WO | disclosed |