Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20069609 | 0.80 | RET (0.42) | SLC6A2SLC6A4SLC6A3ADRB2ALDH1A1 | |
| SCHEMBL1035119 | 0.79 | PPIA (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB2 | |
| SCHEMBL5167704 | 0.72 | SMN1; SMN2 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB2 | |
| SCHEMBL8125084 | 0.72 | ALDH1A1 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB2 | |
| SCHEMBL5310455 | 0.70 | TACR1 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB2 | |
| SCHEMBL5168846 | 0.70 | GRM2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB2 | |
| SCHEMBL22856990 | 0.69 | RET (0.45) | CYP2D6ADRB2ALDH1A1HTTDPP4 | |
| SCHEMBL6180854 | 0.69 | CHRM3 (0.47) | — | |
| SCHEMBL7904502 | 0.69 | ADRB2 (0.48) | CYP2D6ADRB2ALDH1A1HTTDPP4 | |
| SCHEMBL19613626 | 0.68 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070684-A2 | PEPTIDOMIMETIC LIGANDS FOR CELLULAR RECEPTORS AND ION CHANNELS | SEPRACOR, INC. (US) | 2001-09-27 | — | — | WO | disclosed |