Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 9/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1036882 | 0.71 | HCRTR1 (0.53) | OXTRAVPR1AAVPR2HCRTR1HCRTR2 | |
| SCHEMBL6183591 | 0.68 | KMT2A (0.39) | OXTRAVPR2MEN1KMT2ATRPM8 | |
| SCHEMBL1035908 | 0.68 | KDM4E (0.56) | MEN1KMT2ANPC1MAPTSLC22A12 | |
| SCHEMBL38656126 | 0.66 | NNMT (0.49) | OXTRNNMTMEN1KMT2ANPC1 | |
| SCHEMBL22285418 | 0.65 | NNMT (0.47) | NNMTMEN1KMT2ANPC1MAPT | |
| SCHEMBL14566915 | 0.64 | NOS3 (0.41) | KMT2ANPC1RAB9ACYP2A6 | |
| SCHEMBL5091423 | 0.64 | NNMT (0.46) | NNMTMEN1KMT2ANPC1MAPT | |
| SCHEMBL1515571 | 0.63 | NNMT (0.46) | NNMTNPC1MAPTRAB9AMKNK1 | |
| SCHEMBL363152 | 0.62 | KCNN4 (0.45) | OXTRNNMTMEN1KMT2ANPC1 | |
| SCHEMBL22079377 | 0.62 | NNMT (0.48) | NNMTMEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554239-A2 | SULFONYLAMINO-ACETIC ACID DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004033418-A2 | SULFONYLAMINO-ACETIC DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2004-04-22 | — | — | WO | disclosed |