Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190022 | 0.93 | L3MBTL1 (0.60) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL2637137 | 0.78 | KDM4E (0.56) | MEN1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL8407276 | 0.78 | KDM4E (0.56) | MEN1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL16660444 | 0.78 | POLB (0.62) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL962133 | 0.77 | OPRM1 (0.62) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| Cadaverine Tartrate SCHEMBL27494138 | 0.77 | KDM4E (0.50) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL8580878 | 0.77 | KDM4E (0.55) | MEN1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL8184329 | 0.74 | KMT2A (0.54) | L3MBTL1MEN1KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7841617 | 0.73 | LMNA (0.43) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL7841619 | 0.73 | KMT2A (0.44) | L3MBTL1MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441718-A4 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1441718-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | Endo Pharmaceuticals Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003032910-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC. (US) | 2003-04-24 | — | — | WO | disclosed |