Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185847 | 0.93 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL16660444 | 0.85 | POLB (0.62) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL962133 | 0.84 | OPRM1 (0.62) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8184329 | 0.81 | KMT2A (0.54) | L3MBTL1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL13278520 | 0.79 | OPRM1 (0.51) | MEN1KMT2AALDH1A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL7841619 | 0.79 | KMT2A (0.44) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL13278418 | 0.78 | MAPT (0.59) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL16111685 | 0.78 | OPRM1 (0.56) | MEN1KMT2AALDH1A1LMNAOPRM1 | |
| Hydrochloric Acid SCHEMBL7841617 | 0.77 | LMNA (0.43) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL13278434 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441718-A4 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1441718-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | Endo Pharmaceuticals Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003032910-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC. (US) | 2003-04-24 | — | — | WO | disclosed |