Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31583298 | 0.79 | BCAT2 (0.51) | BCAT2CHEK1ALOX5APFEN1SCN9A | |
| SCHEMBL6184315 | 0.78 | NR1H2 (0.56) | SCN9AKDM4EALDH1A1PARP1 | |
| SCHEMBL6187171 | 0.78 | BCAT2 (0.50) | BCAT2CHEK1ALOX5APFEN1SCN9A | |
| SCHEMBL27635470 | 0.78 | BCAT2 (0.63) | BCAT2CHEK1ALOX5APFEN1SCN9A | |
| SCHEMBL5494348 | 0.77 | MAPK8 (0.51) | BCAT2CHEK1MAPK8MAPK10PDK2 | |
| SCHEMBL6763655 | 0.77 | BCAT2 (0.43) | BCAT2CHEK1ALOX5APFEN1SCN9A | |
| SCHEMBL29832438 | 0.76 | PDE3B (0.51) | ALOX5APFEN1SCN9AKDM4EALDH1A1 | |
| SCHEMBL6763651 | 0.76 | BCAT2 (0.42) | BCAT2CHEK1ALOX5APFEN1SCN9A | |
| SCHEMBL27635469 | 0.75 | BCAT2 (0.62) | BCAT2CHEK1PPARGALOX5APFEN1 | |
| SCHEMBL28260267 | 0.73 | BCAT2 (0.45) | BCAT2CHEK1ALOX5APFEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572686-A1 | ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | Novartis AG (CH) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052884-A1 | ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | NOVARTIS AG (CH) | 2004-06-24 | — | — | WO | claimed |