Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31583298 | 0.78 | BCAT2 (0.51) | BCAT2CHEK1ALOX5APFEN1PARP1 | |
| SCHEMBL6187361 | 0.77 | BCAT2 (0.44) | BCAT2CHEK1ALOX5APFEN1SIRT2 | |
| SCHEMBL27635469 | 0.74 | BCAT2 (0.62) | BCAT2CHEK1ALOX5APFEN1PARP1 | |
| SCHEMBL27635470 | 0.74 | BCAT2 (0.63) | BCAT2CHEK1ALOX5APFEN1SCN9A | |
| SCHEMBL6187171 | 0.74 | BCAT2 (0.50) | BCAT2CHEK1ALOX5APFEN1PARP1 | |
| SCHEMBL6763651 | 0.72 | BCAT2 (0.42) | BCAT2CHEK1ALOX5APFEN1PARP1 | |
| SCHEMBL5494348 | 0.71 | MAPK8 (0.51) | BCAT2CHEK1PDK2RORB | |
| SCHEMBL3262902 | 0.70 | ALDH1A1 (0.45) | BCAT2SIRT2CYP3A4 | |
| SCHEMBL28260267 | 0.70 | BCAT2 (0.45) | BCAT2CHEK1ALOX5APFEN1CYP3A4 | |
| SCHEMBL3234092 | 0.70 | ALOX5AP (0.60) | BCAT2CHEK1ALOX5APFEN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023290-A1 | Novel therapeutic agents that modulate enzymatic processes | THERAVANCE BIOPHARMA R&D IP, LLC | 2004-02-05 | — | — | US | disclosed |
| US-20020028943-A1 | Multibinding inhibitors of microsomal triglyceride transferase protein | THERAVANCE BIOPHARMA R&D IP, LLC | 2002-03-07 | — | — | US | disclosed |
| US-6288234-B1 | FLUORINATED HETEROCYCLIC AMIDO AMINE COMPOUNDS AS DRUGS | ADVANCED MEDICINE, INC. | 2001-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028943-A1 | Multibinding inhibitors of microsomal triglyceride transferase protein | MTTP, CETP, HDLBP | BCAT2 887/4885CHEK1 3386/4885ALOX5AP 3441/4885 |
| US-20040023290-A1 | Novel therapeutic agents that modulate enzymatic processes | RNASE1, ENGASE, ENTPD5 | BCAT2 1798/4885CHEK1 2644/4885ALOX5AP 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.