Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188556 | 0.82 | DHFR (0.33) | HTTDHFRHSD11B1 | |
| SCHEMBL6188956 | 0.77 | GAA (0.46) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL6188581 | 0.76 | RECQL (0.40) | LMNA | |
| SCHEMBL8205525 | 0.70 | ACACB (0.34) | DHFRMEN1KMT2A | |
| SCHEMBL8205526 | 0.70 | NPSR1 (0.35) | DHFRMEN1KMT2ANPSR1 | |
| SCHEMBL23704909 | 0.70 | RXRA (0.43) | HTTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8209894 | 0.70 | DHFR (0.38) | DHFRMEN1KMT2AHSD11B1L3MBTL1 | |
| SCHEMBL28450438 | 0.69 | HPGD (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6190860 | 0.69 | DHFR (0.39) | DHFRMEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL6190273 | 0.68 | S1PR3 (0.38) | DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-B1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-6352982-B1 | TREATING DIABETES, OBESITY, OR INVETERATE DIARRHEA IN A MAMMAL WHICH COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND OF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-05 | — | — | US | disclosed |