Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190860 | 0.77 | DHFR (0.39) | DHFRHSD11B1MEN1KMT2AHPGD | |
| SCHEMBL15654560 | 0.73 | MEN1 (0.47) | DHFRCREBBPHSD11B1MEN1KMT2A | |
| SCHEMBL3905489 | 0.72 | CA12 (0.46) | HSD11B1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL4119366 | 0.72 | MAOB (0.40) | DHFRCREBBPHSD11B1MEN1KMT2A | |
| SCHEMBL6908438 | 0.72 | GAA (0.41) | DHFRCREBBPHSD11B1MEN1KMT2A | |
| SCHEMBL8771671 | 0.71 | KDM4E (0.45) | MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL8205627 | 0.71 | SLC6A3 (0.34) | DHFRKMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL29793522 | 0.71 | DHFR (0.44) | DHFRHSD11B1MEN1KMT2AICAM1 | |
| SCHEMBL3038070 | 0.71 | DHFR (0.44) | DHFRHSD11B1MEN1KMT2ATNK2 | |
| SCHEMBL22789783 | 0.70 | ACMSD (0.48) | DHFRHSD11B1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |