Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.34 |
| ▸ | ACACA | Q13085 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205526 | 0.82 | NPSR1 (0.35) | ACACBACACAMEN1KMT2ADHFR | |
| SCHEMBL8198952 | 0.78 | SYK (0.39) | ACACBACACAPPARGPPARDPPARA | |
| SCHEMBL6188559 | 0.75 | DHFR (0.34) | ACACBMEN1KMT2AS1PR3DHFR | |
| SCHEMBL8197944 | 0.71 | AAK1 (0.40) | ACACBACACAPPARGPPARDPPARA | |
| SCHEMBL6188700 | 0.70 | HTT (0.38) | MEN1KMT2ADHFR | |
| SCHEMBL6190273 | 0.68 | S1PR3 (0.38) | S1PR3CREBBPDHFR | |
| SCHEMBL11767308 | 0.67 | ELANE (0.52) | PPARAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5727243 | 0.66 | PKM (0.46) | MEN1KMT2ADHFR | |
| SCHEMBL10830970 | 0.66 | TAS1R3 (0.37) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL8211448 | 0.66 | DHFR (0.36) | S1PR3DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |